Degrassi:The Next Generation
drama
The N, Fridays, 8 PM
http://www.the-n.com/ntv/shows/index.php?id=67

Gay teen Marco Del Rossi (Adamo Ruggiero) is heading to college with the rest of the crew, including Alex Nuñez (Deanna Casaluce) who came out at the end of last season.

Desperate Housewives
drama
ABC, Sundays, 9 PM
http://abc.go.com/primetime/desperate/index.html

Andrew Van de Kamp (Shawn Pyfrom) is the rebel of Wysteria Lane.

Dirt
drama
FX, Tuesdays, 10 PM
http://www.fxnetworks.com/shows/originals/dirt/

Leo Spiller (Will McCormack) is tabloid editor Lucy Spiller's (Courteney Cox, not pictured) gay brother.

Entourage
comedy
HBO, Sundays, 10 PM
http://www.hbo.com/entourage/

Lloyd (Rex Lee) is Ari Gold's tortured assistant.

ER
drama
NBC, Thursdays, 10 PM
http://www.nbc.com/ER/

Lesbian hospital administrator Dr. Kerry Weaver (Laura Innes) is raising her son after the death of her partner.

Fashion House
drama
MyNetworkTV (aired one season)
http://www.mynetworktv.com/fh.html

Harold (Garrett Swann, left) and Hans (Toni Tripoli, right) are designers caught in a war between dueling fashion divas.

Help Me Help You
comedy
ABC, Tuesdays (aired one season)
http://abc.go.com/primetime/schedule/2006-07/helpmehelpyou.html

Jonathan (Jim Rash) is a closeted married man attending group therapy sessions.

Mile High
comedy
BBC America, Returns in fall
http://bbcamerica.com/genre/drama_mysteries/mile_high/mile_high.jsp

Will (Adam Sinclair) is a flamboyant flight attendant working for Fresh, a budget airline.

Nip/Tuck
drama
FX, Returns in fall
http://www.fxnetworks.com/shows/originals/niptuck/main.html

Liz Cruz (Roma Maffia) is a lesbian anesthesiologist for a cosmetic surgery practice in Miami.

The Office
comedy
NBC, Thursdays, 8:30 PM
http://www.nbc.com/The_Office/

Oscar (Oscar Nuñez) is a gay accountant for the Dunder-Mifflin paper supply company in Scranton.

Rescue Me
drama
FX, returns in June
http://www.fxnetworks.com/shows/originals/rescueme/

Mike "Probie" Silletti (Mike Lombardi) has been involved in a sexual relationship with his male roommate, but dates women as well, and does not consider himself to be gay in the slightest.

Saints and Sinners
drama
MyNetworkTV, Wednesdays, 9 PM
http://www.mynetworktv.com/saints_and_sinners.html

Evan (Shelli Boone) is a lesbian who works at the hotel and is best friends with Sloane (Roslie Ward, not pictured).

Saved
Drama
TNT (aired one season)
http://alt.tnt.tv/saved/saved.shtml

Angela de la Cruz (Tracy Vilar) is a lesbian paramedic.

The Shield
drama
FX, Tuesdays, 10 PM
http://www.fxnetworks.com/shows/originals/the_shield/main.html

Julien Lowe (Michael Jace) is a deeply religious, African American police officer struggling to repress his sexual orientation. Everyone in his squad knows that he is gay, but after completing a church program that promised to "cure homosexuality," Julien married a woman and adopted her son. However, Julien's story is not yet finished and there are signs that his "cure" has not been entirely successful.

The Simpsons
animated comedy
Fox, Sundays, 8 PM
http://www.thesimpsons.com/

Waylon Smithers (Hank Azaria) is Mr. Burns' right-hand-man.

Ugly Betty
comedy
ABC, Thursdays, 8 PM
http://abc.go.com/primetime/schedule/2006-07/betty.html

Marc (Michael Urie) is an assistant working for Mode magazine. Alexis (Rebecca Romijn) is a member of the Meade publishing family who recently underwent gender reassignment surgery.

The War at Home
comedy
Fox, Sundays, 9:30 PM
http://fox.com/warathome/

Larry's best friend Kenny (Rami Malek) is a closeted gay teen.

Watch Over Me
drama
MyNetworkTV, Mondays-Fridays, 9 PM
http://www.mynetworktv.com/watch_over_me.html

Andre (Casper Van Dien) is a hired assassin who keeps his personal life hidden from his boss — and he can't fight his feelings for Ryan (Omar Avilla, right).

What Goes On
drama
The N, premieres in 2007
http://www.the-n.com/

Sasha (Edward Tournier) is a gay teen who falls for another student, hoping to develop a relationship with him.

The Wire
drama
HBO, returns in 2008
http://www.hbo.com/thewire/

Shakima Greggs (Sonja Sohn) is an ambitious, African American lesbian cop. Omar (Michael K. Williams) is a gay thief who steals from drug dealers.