Big Day
comedy
ABC, (aired one season)
http://abc.go.com/primetime/schedule/2006-07/bigday.html

On his best friend's wedding day, Fred (Leslie Odom, Jr.) realizes he has feelings for the groom.

Brotherhood
drama
Showtime, returns in fall
http://www.sho.com/site/brotherhood/home.do

Alex (Karl Bury, pictured) is politician Tommy Caffee's (Jason Clarke) chief of staff.

ER
drama
NBC
Thursdays, 10 PM
http://www.nbc.com/ER/

Chaz Pratt (Sam Jones III) the gay half-brother of Dr. Gregory Pratt (Mekhi Phifer, not pictured).

Friday Night Lights
drama
NBC, Wednesdays, 8 PM
http://www.nbc.com/Friday_Night_Lights/

Lucy Rodell (Libby Villari) is the closeted Mayor of Dillon, Texas.

Grey's Anatomy
drama
ABC, Thursdays, 9 PM
http://abc.go.com/primetime/greysanatomy/index.html

All the interns of Seattle Grace Hospital hang out at Emerald City Bar, owned by gay bartender Joe (Steven W. Bailey).

Hidden Palms
drama
The CW, premiers in spring
http://cwtv.com/

Jesse Jo (Leslie Jordan) is a gay AA sponsor in Palm Springs.

The Minor Accomplishments of Jackie Woodman
comedy
IFC, (aired one season)
http://ifc.com/

Jackie Woodman (Laura Kightlinger) is an aspiring screenwriter who writes for a second-rate magazine called Image, where Mitchell (Patrick Bristow), a gay writer, works. Connor (Butch Klein, not pictured) is Jackie's best friend's closeted boyfriend.

Saved
Drama
TNT (aired one season)
http://alt.tnt.tv/saved/saved.shtml

Misha (Christopher Redman) is Wyatt's loan shark.

The Simpsons
animated comedy
Fox, Sundays, 8 PM
http://www.thesimpsons.com/

Springfield houses lesbian and gay citizens, including Marge's sister, Patty Bouvier (Julie Kavner).

The War at Home
comedy
Fox, Sundays, 7:30 PM
http://fox.com/warathome/

Larry's best friend Kenny (Rami Malek) is a closeted gay teen.

Weeds
comedy
Showtime, Returns in June
http://www.sho.com/site/weeds/home.do

Young Isabelle (Allie Grant) has told her mother Celia (Elizabeth Perkins), that she's a lesbian.

The Wire
drama
HBO, Returns in 2008
http://www.hbo.com/thewire/

Deputy Commissioner for Operations William A. Rawls (John Doman) was spotted at a gay bar last season, but he is quiet about his personal life with other officers.